Research & Studies

Many people use CBD as part of a healthy lifestyle to promote wellness in a variety of areas. The FDA has not yet approved CBD for specific ailments or conditions. However, leading researchers have already held CBD clinical studies and  its effect on the body.

Anxiety Related Disorders:

Journal of Current Neruopharmacology.  Evidences for the Anti-panic Actions of Cannabidiol.  2017 Feb; 15(2): 291-299

Journal of Basic Clinical Physiology Pharmacology.  Targeting the endocannabinoid system to treat anxiety-related disorders.  (particularly PTSD) 2016; 27(3); 193-202

Journal of Neurotherapeutics.  Cannabidiol as a Potential Treatment for Anxiety disorders.  2015 Oct; 12(4) 825-836

Neuropsychopharmacology.  Cannabidiol Reduces the Anxiety Induced by Simulated Public speaking in Treatment-Naive Social Phobia Patients.  2011 May 36(6) 1219-1226.

Anesthesia and Analgesia.  Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57B16 Mice.  2011 Oct 113(4) 947-950

Anxiety:

The Permanente Journal.  Cannabidiol in Anxiety and Sleep:  A Large Class Study. 2019 Jan 7 23: 18-041

Depressive Symptoms:

Journal of Neuropharmacology.  Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutimate neurotransmission:  Role of 5-HT1A receptor. 2016 Apr 16-26.

Traumatic Brain Injury:

Frontiers in Pharmacology.  Endocannibinoids: A Promising Impact for Traumatic Brain Injury  2017: 8:69

Neuroprotection:

Journal of Pharmacological Experimental Therapies.  Comparison of Cannabidol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxcity.  2005 August 314(2) 780-788.

US Patent #6630507.  Title: Cannabinoids and Antioxidants as Neuroprotectants.  1999. Hampson, Axelrod, Grimaldi. The focus of this study is the neuroprotective role of cannabinoids, particularly cannabidol, in neurodegenerative conditions including stroke, traumatic brain injury, alzheimers, parkinsons, and HIV dementia.   

Pain, Neurotoxicity, and Inflammation:

British Journal of Pharmacology.  Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT1A receptors without diminishing nervous system function or chemotherapy efficacy.  2014: 171 636-645

Pain.  The putative cannabinoid receptor GPR55 plays a role in hyperalgesia associated with inflammatory and neuropathic pain. 2008

Journal of Therapeutics and Clinical Risk Management.  Cannabinoids in the management of difficult to treat pain.  2008: Feb 8 4(1) 245-259

Journal of Cellular Immunology.  The non-psychoactive phytocannabinoid cannabidiol (CBD) attenuates pro-inflammatory mediators, T cell infiltration, and thermal sensitivity following spinal cord injury in mice.  2018: 329 1-9

Arthritis:

PAIN.  Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis.  2017 Dec 158(12) 2442-2451

Recovery From Substance Abuse:

Journal of Substance Abuse Research and Treatment.  Cannabidiol as an Intervention for Addictive Behaviors.  A Systematic Review of the Evidence. 2015: 9 33-38

Journal of Pharmacological Experimental Therapies.  Comparison of Cannabidol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxcity.  2005 August 314(2) 780-788.

Epilepsy and Seizures:

The Journal of Pharmacology and Experimental Therapeutics. Cannabidiol displays anti-epileptiform and anti-seizure properties invitro and invivo.  2010 Feb: 332(2) 569-577

Schizophrenia:  

Journal of Psychopharmacology.  Cannabidiol effects in the prepulse inhibition disruption induced by amphetamine.  2015 Aug: 232(16) 3057-65.